A2ml1 Gene Summary [Mouse]

Predicted to enable serine-type endopeptidase inhibitor activity. Part of protein-containing complex. Is expressed in several structures, including central nervous system; hemolymphoid system gland; smooth muscle tissue; stomach; and uterus. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
A2ml1
Official Name
alpha-2-macroglobulin like 1 [Source:MGI Symbol;Acc:MGI:3039594]
Ensembl ID
ENSMUSG00000047228
Bio databases IDs NCBI: 232400 Ensembl: ENSMUSG00000047228
Aliases alpha-2-macroglobulin like 1
Synonyms alpha-2-macroglobulin-like 1, BC048546, Ovos, Ovos2, RGD1565709, α-2-macroglobulin-like 1
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse A2ml1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Alpha-2-macroglobulin bait region domain
  • ISOPREN_C2_like
  • Macroglobulin domain MG4
  • A-macroglobulin TED domain
  • A-macroglobulin receptor binding domain
  • Alpha-2-macroglobulin family
  • MG2 domain
  • Macroglobulin domain MG3

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
phenotypes
  • preweaning lethality incomplete penetrance

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.