8030462N17Rik Gene Summary [Mouse]

Predicted to enable transcription corepressor activity and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of viral life cycle and ubiquitin-dependent protein catabolic process. Predicted to be located in chromatin. Orthologous to human ARK2N (arkadia (RNF111) N-terminal like PKA signaling regulator 2N). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
8030462N17Rik
Official Name
RIKEN cDNA 8030462N17 gene [Source:MGI Symbol;Acc:MGI:2444951]
Ensembl ID
ENSMUSG00000047466
Bio databases IDs NCBI: 212163 Ensembl: ENSMUSG00000047466
Aliases RIKEN cDNA 8030462N17 gene
Synonyms 8030462N17Rik, AC102195.3, Akd2, arkadia (RNF111) N-terminal like PKA signaling regulator 2N, ARKL1, C18orf25, LOC100909715, RGD1308601, RNF111L1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse 8030462n17rik often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • transcription co-repressor
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • osteoarthropathy
  • erythema
regulated by
regulates
role in cell
  • phosphorylation in
  • activation
  • loss
  • ubiquitination in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • chromatin

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse 8030462n17rik gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription, DNA-dependent
  • ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • chromatin

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • transcription corepressor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.