C18orf25 Gene Summary [Human]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | C18orf25 |
| Official Name | chromosome 18 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:28172] |
| Ensembl ID | ENSG00000152242 |
| Bio databases IDs | |
| Aliases | chromosome 18 open reading frame 25, ARKadia-like 1 |
| Synonyms | 8030462N17Rik, AC102195.3, Akd2, arkadia (RNF111) N-terminal like PKA signaling regulator 2N, ARKL1, C18orf25, LOC100909715, RGD1308601, RNF111L1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C18orf25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-repressor
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C18orf25 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription corepressor activity