Ddi1 Gene Summary [Mouse]
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in several processes, including cellular response to hydroxyurea; regulation of DNA stability; and regulation of protein stability. Is expressed in brain and future brain. Orthologous to human DDI1 (DNA damage inducible 1 homolog 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddi1 |
| Official Name | DNA-damage inducible 1 [Source:MGI Symbol;Acc:MGI:1919079] |
| Ensembl ID | ENSMUSG00000047619 |
| Bio databases IDs | |
| Aliases | DNA-damage inducible 1 |
| Synonyms | 1700011N24Rik, DNA-damage inducible 1, DNA-damage inducible 1 homolog 1, RGD1559430, Riken cDNA 1700011n24 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddi1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquitin family
- Ubl1_cv_Nsp3_N-like
- Ubiquitin homologues
- protein binding
- Cellular and retroviral pepsin-like aspartate proteases
- gag-polyprotein putative aspartyl protease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ddi1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein stability
- cellular response to hydroxyurea
- proteasomal protein catabolic process
Molecular Function
What the gene product does at the molecular level
- aspartic-type endopeptidase activity
- protein binding