Phf13 Gene Summary [Mouse]
Predicted to enable chromatin binding activity; chromatin-protein adaptor activity; and methylated histone binding activity. Predicted to be involved in mitotic chromosome condensation and regulation of DNA repair. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; ganglia; genitourinary system; and sensory organ. Orthologous to human PHF13 (PHD finger protein 13). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Phf13 |
| Official Name | PHD finger protein 13 [Source:MGI Symbol;Acc:MGI:2446217] |
| Ensembl ID | ENSMUSG00000047777 |
| Bio databases IDs | |
| Aliases | PHD finger protein 13 |
| Synonyms | PHD finger protein 13, PHF5, SPOC1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Phf13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PHD zinc finger
- histone binding
- protein binding activity, bridging
- PHD finger superfamily
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Phf13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- mitotic chromosome condensation
- regulation of DNA repair
- chromosome segregation
- chromatin organization
- mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- methylated histone residue binding
- chromatin binding