Spata33 Gene Summary [Mouse]
Involved in mitophagy. Acts upstream of or within fertilization; flagellated sperm motility; and protein localization. Located in male germ cell nucleus; mitochondrion; and sperm mitochondrial sheath. Orthologous to human SPATA33 (spermatogenesis associated 33). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spata33 |
| Official Name | spermatogenesis associated 33 [Source:MGI Symbol;Acc:MGI:2444920] |
| Ensembl ID | ENSMUSG00000048478 |
| Bio databases IDs | |
| Aliases | spermatogenesis associated 33 |
| Synonyms | 4732415M23Rik, AI847264, C16orf55, RGD1561507, spermatogenesis associated 33 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spata33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Domain of unknown function (DUF4609)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- sperm midpiece
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spata33 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- macromitophagy
Cellular Component
Where in the cell the gene product is active
- nucleus
- sperm midpiece
- cytoplasm
- mitochondrion
- sperm mitochondrial sheath
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding