Vstm2a Gene Summary [Mouse]
Enables identical protein binding activity. Involved in several processes, including cellular response to BMP stimulus; positive regulation of brown fat cell differentiation; and positive regulation of white fat cell proliferation. Located in extracellular region. Is expressed in central nervous system; head mesenchyme; hindlimb mesenchyme; and jaw bone. Orthologous to human VSTM2A (V-set and transmembrane domain containing 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vstm2a |
| Official Name | V-set and transmembrane domain containing 2A [Source:MGI Symbol;Acc:MGI:2384826] |
| Ensembl ID | ENSMUSG00000048834 |
| Bio databases IDs | |
| Aliases | V-set and transmembrane domain containing 2A |
| Synonyms | LOC100364156, LOC102546914, RGD1308957, V-set and transmembrane domain containing 2A, VSTM2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vstm2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin V-Type
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- identical protein binding
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Vstm2a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of brown fat cell differentiation
- cellular response to BMP stimulus
- positive regulation of gene expression
- positive regulation of white fat cell proliferation
- cell differentiation
- positive regulation of lipid storage
Cellular Component
Where in the cell the gene product is active
- nucleus
- membrane
- extracellular region
Molecular Function
What the gene product does at the molecular level
- identical protein binding