Bmyc Gene Summary [Mouse]
Enables molecular adaptor activity. Predicted to be involved in several processes, including ERK1 and ERK2 cascade; regulation of fibroblast proliferation; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of with a positive effect on negative regulation of gene expression via chromosomal CpG island methylation. Located in spindle. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bmyc |
| Official Name | brain expressed myelocytomatosis oncogene [Source:MGI Symbol;Acc:MGI:88184] |
| Ensembl ID | ENSMUSG00000049086 |
| Bio databases IDs | |
| Aliases | brain expressed myelocytomatosis oncogene |
| Synonyms | 2900002K07Rik, brain expressed myelocytomatosis oncogene, Homolog to b-myc transforming, Mycb |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bmyc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity
- RNA polymerase II transcription factor activity, sequence-specific DNA binding
- transcription regulator
- RNA polymerase II transcription regulatory region sequence-specific binding transcriptional repressor activity
- binding protein
- nucleic acid binding
- double-stranded DNA binding
- transcription factor binding
- sequence-specific DNA binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasmic fraction
- spindle apparatus
- nucleoplasm
- nucleoli
- chromatin
- cytoplasmic fraction