Bdp1 Gene Summary [Mouse]
Predicted to enable TFIIIC-class transcription factor complex binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of transcription factor TFIIIB complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 112. Orthologous to human BDP1 (BDP1 general transcription factor IIIB subunit). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bdp1 |
| Official Name | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB [Source:MGI Symbol;Acc:MGI:1347077] |
| Ensembl ID | ENSMUSG00000049658 |
| Bio databases IDs | |
| Aliases | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB |
| Synonyms | AI662220, B130055N23RIK, B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB, BDP1 general transcription factor IIIB subunit, DFNB112, G630013P12RIK, HSA238520, mKIAA1241, TAF3B1, TFC5, TFIIIB'', TFIIIB150, TFIIIB90, TFNR |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bdp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Myb DNA-binding like
- protein binding
Pathways
Biological processes and signaling networks where the Bdp1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- granules
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bdp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA polymerase III transcriptional preinitiation complex assembly
Cellular Component
Where in the cell the gene product is active
- transcription factor TFIIIB complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- TFIIIC-class transcription factor binding
- protein binding