Micos13 Gene Summary [Mouse]
Predicted to be involved in cristae formation. Located in mitochondrion. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 37. Orthologous to human MICOS13 (mitochondrial contact site and cristae organizing system subunit 13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Micos13 |
| Official Name | mitochondrial contact site and cristae organizing system subunit 13 [Source:MGI Symbol;Acc:MGI:2442174] |
| Ensembl ID | ENSMUSG00000049760 |
| Bio databases IDs | |
| Aliases | mitochondrial contact site and cristae organizing system subunit 13 |
| Synonyms | 2410015M20Rik, C19orf70, MIC12, MIC13, mitochondrial contact site and cristae organizing system subunit 13, P117, QIL1, sr104 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Micos13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MICOS complex subunit MIC13, QIL1
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
- nucleoplasm
- organelle membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Micos13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cristae formation
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- mitochondrial crista junction
- mitochondrion
- mitochondrial sorting and assembly machinery complex
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding