Mfsd4a Gene Summary [Mouse]
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Orthologous to human MFSD4A (major facilitator superfamily domain containing 4A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfsd4a |
| Official Name | major facilitator superfamily domain containing 4A [Source:MGI Symbol;Acc:MGI:2442786] |
| Ensembl ID | ENSMUSG00000059149 |
| Bio databases IDs | |
| Aliases | major facilitator superfamily domain containing 4A |
| Synonyms | A230072B04, A930031D07Rik, DKFZp761N1114, major facilitator superfamily domain containing 4A, MFSD4, RGD1566090, SLC60A1, UNQ3064 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfsd4a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Major Facilitator Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- lung adenocarcinoma formation
- EGFR mutation positive adenocarcinoma of the lung
- EGFR mutation positive non-small cell lung cancer
- EGFR expression positive non-squamous non-small cell lung cancer
regulated by
- VEGF
- IL10RA
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfsd4a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- glucose transmembrane transporter activity