Tmem17 Gene Summary [Mouse]
Involved in cilium assembly and smoothened signaling pathway. Located in ciliary membrane and ciliary transition zone. Part of MKS complex. Orthologous to human TMEM17 (transmembrane protein 17). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem17 |
| Official Name | transmembrane protein 17 [Source:MGI Symbol;Acc:MGI:2144205] |
| Ensembl ID | ENSMUSG00000049904 |
| Bio databases IDs | |
| Aliases | transmembrane protein 17 |
| Synonyms | AI503894, transmembrane protein 17 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Predicted membrane protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- ciliary transition zone
- cilia
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- smoothened signaling pathway
Cellular Component
Where in the cell the gene product is active
- cilium membrane
- ciliary transition zone
- TCTN-B9D complex
Molecular Function
What the gene product does at the molecular level
- protein binding