Lrrc25 Gene Summary [Mouse]

Acts upstream of or within several processes, including canonical NF-kappaB signal transduction; connective tissue replacement involved in inflammatory response wound healing; and response to angiotensin. Predicted to be located in cytosol; endoplasmic reticulum; and microtubule cytoskeleton. Orthologous to human LRRC25 (leucine rich repeat containing 25). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lrrc25
Official Name
leucine rich repeat containing 25 [Source:MGI Symbol;Acc:MGI:2445284]
Ensembl ID
ENSMUSG00000049988
Bio databases IDs NCBI: 211228 Ensembl: ENSMUSG00000049988
Aliases leucine rich repeat containing 25
Synonyms leucine rich repeat containing 25, MAPA, RGD1564818
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TM_EGFR-like
  • Leucine rich repeat
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gout
  • hyperemesis gravidarum
regulated by
  • tretinoin
  • deferoxamine
  • TGM2
  • deferasirox
  • cholecalciferol
  • TFRC

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • microtubule cytoskeleton
  • cellular membrane
  • Endoplasmic Reticulum
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc25 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • microtubule cytoskeleton
  • membrane
  • cytosol
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.