Pnma5 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Involved in meiosis I. Acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction. Is active in cell cortex and meiotic spindle. Orthologous to human PNMA5 (PNMA family member 5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pnma5
Official Name
paraneoplastic antigen family 5 [Source:MGI Symbol;Acc:MGI:2180566]
Ensembl ID
ENSMUSG00000050424
Bio databases IDs NCBI: 385377 Ensembl: ENSMUSG00000050424
Aliases paraneoplastic antigen family 5
Synonyms Hs.469593, LOC108167389, mKIAA1934, paraneoplastic antigen family 5, PNMA family member 5, RGD1565857
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pnma5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PNMA
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cell cortex
  • Nucleus
  • meiotic spindles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pnma5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of apoptotic process

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.