Lamtor4 Gene Summary [Mouse]
Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization to lysosome. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of FNIP-folliculin RagC/D GAP and Ragulator complex. Predicted to be active in lysosomal membrane. Is expressed in brain and retina layer. Orthologous to human LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lamtor4 |
| Official Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 [Source:MGI Symbol;Acc:MGI:1913346] |
| Ensembl ID | ENSMUSG00000050552 |
| Bio databases IDs | |
| Aliases | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 |
| Synonyms | 0910001L09Rik, C7orf59, late endosomal/lysosomal adaptor, MAPK and MTOR activator 4, RGD1309735 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lamtor4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- guanyl-nucleotide exchange factor
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- lysosome
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lamtor4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to amino acid stimulus
- regulation of cell size
- positive regulation of TOR signaling cascade
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- intracellular membrane-bounded organelle
- Ragulator complex
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- guanyl-nucleotide exchange factor activity
- binding, bridging