Kctd16 Gene Summary [Mouse]
Predicted to enable G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within behavioral fear response; memory; and regulation of G protein-coupled receptor signaling pathway. Located in postsynaptic membrane and presynaptic membrane. Part of receptor complex. Is expressed in autopod; central nervous system; dorsal root ganglion; sensory organ; and trachea. Orthologous to human KCTD16 (potassium channel tetramerization domain containing 16). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kctd16 |
| Official Name | potassium channel tetramerisation domain containing 16 [Source:MGI Symbol;Acc:MGI:1914659] |
| Ensembl ID | ENSMUSG00000051401 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerisation domain containing 16 |
| Synonyms | 2900055J20Rik, 4930434H12Rik, AC127249.1, C030017B01Rik, Gm1267, potassium channel tetramerisation domain containing 16, potassium channel tetramerization domain containing 16, RGD1559856 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kctd16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- H1 domain found in potassium channel tetramerization domain-containing proteins
- neurotransmitter receptor
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- presynaptic membrane
- postsynaptic membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kctd16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein homooligomerization
- regulation of G-protein coupled receptor protein signaling pathway
Cellular Component
Where in the cell the gene product is active
- presynaptic membrane
- postsynaptic membrane
- receptor complex
- cell projection
Molecular Function
What the gene product does at the molecular level
- protein binding