Trpm3 Gene Summary [Mouse]
Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transport. Is expressed in cochlea; liver; nervous system; and retina. Used to study cataract and microphthalmia. Human ortholog(s) of this gene implicated in cataract. Orthologous to human TRPM3 (transient receptor potential cation channel subfamily M member 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trpm3 |
| Official Name | transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101] |
| Ensembl ID | ENSMUSG00000052387 |
| Bio databases IDs | |
| Aliases | transient receptor potential cation channel, subfamily M, member 3 |
| Synonyms | 6330504P12Rik, 9330180E14, AU018608, B930001P07Rik, LTRPC3, MLSN2, transient receptor potential cation channel, subfamily M, member 3 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trpm3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tetramerization domain of TRPM
- Ion transport protein
- SLOG in TRPM
- calcium channel
- ion channel
- cation channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane