Ccdc18 Gene Summary [Mouse]

Predicted to be located in centriolar satellite. Orthologous to human CCDC18 (coiled-coil domain containing 18). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Ccdc18
Official Name
coiled-coil domain containing 18 [Source:MGI Symbol;Acc:MGI:1922974]
Ensembl ID
ENSMUSG00000056531
Bio databases IDs NCBI: 73254 Ensembl: ENSMUSG00000056531
Aliases coiled-coil domain containing 18
Synonyms 1700021E15Rik, 4932411G06Rik, coiled-coil domain containing 18, LOC100910239, NY-SAR-41, RGD1564165
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccdc18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitotic checkpoint protein
  • Crescentin protein
  • chromosome segregation protein SMC, primarily archaeal type
  • exonuclease SbcC
  • Synaptonemal complex protein 1 (SCP-1)
  • rad50
  • Autophagy protein ATG17-like domain
  • Myosin tail
  • helix-rich Mycoplasma protein
  • Calcium binding and coiled-coil domain (CALCOCO1) like
  • Alpha helical coiled-coil rod protein (HCR)
  • chromosome segregation protein SMC, common bacterial type
  • RecF/RecN/SMC N terminal domain
  • Coiled-coil domain-containing protein 158

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • acute myeloid leukemia
  • chronic lymphocytic leukemia
  • idiopathic scoliosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccdc18 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • centriolar satellite

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.