Cenpq Gene Summary [Mouse]

Predicted to be involved in metaphase chromosome alignment and positive regulation of protein localization to kinetochore. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be part of inner kinetochore. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer; embryo; and otocyst. Orthologous to human CENPQ (centromere protein Q). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cenpq
Official Name
centromere protein Q [Source:MGI Symbol;Acc:MGI:1933744]
Ensembl ID
ENSMUSG00000023919
Bio databases IDs NCBI: 83815 Ensembl: ENSMUSG00000023919
Aliases centromere protein Q
Synonyms 2610528M18Rik, C6orf139, centromere protein Q, LOC100361893
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cenpq often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • CENP-Q, a CENPA-CAD centromere complex subunit

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • MYC mutation positive B-cell lymphoma
  • lymphomagenesis
  • B cell cancer
  • ischemic stroke
regulated by
role in cell
  • cohesion in
  • cohesion
  • chromosomal congression

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • actin cytoskeleton
  • cytosol
  • nucleoplasm
  • kinetochores

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cenpq gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • metaphase plate congression
  • chromosome segregation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • condensed chromosome inner kinetochore
  • actin cytoskeleton
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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