Ado Gene Summary [Mouse]
Enables cysteamine dioxygenase activity and iron ion binding activity. Predicted to be involved in cellular response to hypoxia. Located in mitochondrion. Is expressed in cortical plate. Orthologous to human ADO (2-aminoethanethiol dioxygenase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ado |
| Official Name | 2-aminoethanethiol (cysteamine) dioxygenase [Source:MGI Symbol;Acc:MGI:2685083] |
| Ensembl ID | ENSMUSG00000057134 |
| Bio databases IDs | |
| Aliases | 2-aminoethanethiol (cysteamine) dioxygenase |
| Synonyms | 2-aminoethanethiol dioxygenase, C10orf22, FLJ14547, Gm237, RGD1308233 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ado often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- iron ion binding
- enzyme
- protein binding
- cysteamine dioxygenase
- RmlC-like cupin superfamily
- PCO_ADO
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ado gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to hypoxia
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- iron ion binding
- cysteamine dioxygenase activity