Sh2d4a Gene Summary [Mouse]
Predicted to enable phosphatase binding activity. Located in cytoplasm. Is expressed in medulla oblongata floor plate; metencephalon floor plate; and spinal cord floor plate. Orthologous to human SH2D4A (SH2 domain containing 4A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sh2d4a |
| Official Name | SH2 domain containing 4A [Source:MGI Symbol;Acc:MGI:1919531] |
| Ensembl ID | ENSMUSG00000053886 |
| Bio databases IDs | |
| Aliases | SH2 domain containing 4A |
| Synonyms | 2210402M20Rik, PPP1R38, SH2A, SH2 domain containing 4A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sh2d4a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src homology 2 (SH2) domain
- protein binding
- phosphatase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sh2d4a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- protein binding