Rnf207 Gene Summary [Mouse]

Predicted to enable Hsp70 protein binding activity and transmembrane transporter binding activity. Predicted to be involved in several processes, including positive regulation of delayed rectifier potassium channel activity; regulation of cardiac muscle contraction; and regulation of heart looping. Predicted to be active in perinuclear region of cytoplasm. Orthologous to human RNF207 (ring finger protein 207). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Rnf207
Official Name
ring finger protein 207 [Source:MGI Symbol;Acc:MGI:2684989]
Ensembl ID
ENSMUSG00000058498
Bio databases IDs NCBI: 433809 Ensembl: ENSMUSG00000058498
Aliases ring finger protein 207
Synonyms C1orf188, D330010C22Rik, Gm143, LOC100128518, ring finger protein 207
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf207 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
  • Hsp70 protein binding
  • B-Box C-terminal domain
  • protein binding
  • B-box-type zinc finger superfamily
  • RING-type zinc-finger
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • ion channel binding
  • B-box zinc finger
  • chaperone binding
  • zinc-RING finger domain
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • long-QT syndrome
  • heart failure
  • hypertrophic cardiomyopathy
regulated by
  • oxygen
  • zeaxanthin dipalmitate
  • TSC1
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • perinuclear region

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rnf207 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of gene expression
  • cell-cell signaling involved in cardiac conduction
  • regulation of cardiac muscle contraction

Cellular Component

Where in the cell the gene product is active
  • perinuclear region of cytoplasm

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • chaperone binding
  • ion channel binding
  • Hsp70 protein binding

Gene-Specific Assays for Results You Can Trust

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