Rcan3 Gene Summary [Mouse]

Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity; phosphatase binding activity; and troponin I binding activity. Predicted to be involved in calcium-mediated signaling. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including brain; genitourinary system; immune system; liver; and stomach. Orthologous to human RCAN3 (RCAN family member 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rcan3
Official Name
regulator of calcineurin 3 [Source:MGI Symbol;Acc:MGI:1858220]
Ensembl ID
ENSMUSG00000059713
Bio databases IDs NCBI: 53902 Ensembl: ENSMUSG00000059713
Aliases regulator of calcineurin 3
Synonyms AU041093, Csp3, DSCR1L2, hRCN3, MCIP3, RCAN family member 3, RCN3, regulator of calcineurin 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rcan3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • cytoskeletal protein binding
  • protein binding
  • Calcipressin
  • phosphatase binding
  • RNA binding

Pathways

Biological processes and signaling networks where the Rcan3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • trichostatin A
  • beta-estradiol
  • mir-17 (includes others)
  • RYR1
  • AGN194204
  • lenalidomide
  • MAPK1
  • USP37

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rcan3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • anatomical structure morphogenesis
  • calcium-mediated signaling

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • phosphatase binding
  • protein binding
  • RNA binding
  • troponin I binding
  • calcium-dependent protein serine/threonine phosphatase regulator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.