Snu13 Gene Summary [Mouse]

Enables box C/D sno(s)RNA binding activity. Involved in box C/D snoRNP assembly. Acts upstream of or within single fertilization. Part of box C/D methylation guide snoRNP complex. Is expressed in head. Orthologous to human SNU13 (small nuclear ribonucleoprotein 13). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Snu13
Official Name
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) [Source:MGI Symbol;Acc:MGI:893586]
Ensembl ID
ENSMUSG00000063480
Bio databases IDs NCBI: 20826 Ensembl: ENSMUSG00000063480
Aliases SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
Synonyms 15.5K, FA-1, Fta1, NHP2L1, NHPX, OTK27, small nuclear ribonucleoprotein 13, SNRNP15-5, SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5), SPAG12, SSFA1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snu13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ATPase binding
  • U4 snRNA binding
  • Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
  • U4/U6.U5 small nuclear ribonucleoprotein SNU13
  • snoRNA binding
  • protein binding
  • U4atac snRNA binding

Pathways

Biological processes and signaling networks where the Snu13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • infection by vesicular stomatitis virus
regulated by
  • seocalcitol
  • poly rI:rC-RNA
  • FLI1
  • hexamethylene bisacetamide
  • geldanamycin
  • Major late
  • lnc-SERINC1-8
  • MYCL
role in cell
  • splicing by
  • processing in
  • binding
  • homologous recombination in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • pre-ribosome
  • Plasma Membrane
  • spliceosomes
  • dense fibrillar component
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Snu13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • box C/D snoRNP assembly
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • single fertilization
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • box C/D snoRNP complex
  • small-subunit processome
  • nucleus
  • precatalytic spliceosome
  • U4atac snRNP
  • U4/U6 x U5 tri-snRNP complex
  • macromolecular complex
  • U2-type precatalytic spliceosome
  • nucleolus
  • nucleoplasm
  • dense fibrillar component

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • snoRNA binding
  • box C/D snoRNA binding
  • U3 snoRNA binding
  • U4atac snRNA binding
  • U4 snRNA binding
  • ATPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.