Wdr6

Predicted to enable enzyme regulator activity; insulin receptor substrate binding activity; and tRNA binding activity. Predicted to be involved in negative regulation of autophagy; negative regulation of cell population proliferation; and wobble position ribose methylation. Predicted to act upstream of with a negative effect on G1 to G0 transition. Predicted to be located in cytosol and plasma membrane. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm. Is expressed in nervous system and neural retina. Orthologous to human WDR6 (WD repeat domain 6). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr6 gene, providing context for its role in the cell.