Insyn1 Gene Summary [Mouse]
Involved in inhibitory postsynaptic potential and postsynaptic specialization organization. Located in postsynaptic density. Is active in GABA-ergic synapse and postsynaptic specialization. Orthologous to human INSYN1 (inhibitory synaptic factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Insyn1 |
| Official Name | inhibitory synaptic factor 1 [Source:MGI Symbol;Acc:MGI:2442108] |
| Ensembl ID | ENSMUSG00000066607 |
| Bio databases IDs | |
| Aliases | inhibitory synaptic factor 1 |
| Synonyms | 6030419C18Rik, C15orf59, inhibitory synaptic factor 1, LOC388135, RGD1562618 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Insyn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4589)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- organelle
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Insyn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of inhibitory postsynaptic membrane potential
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
Molecular Function
What the gene product does at the molecular level
- protein binding