Krt77 Gene Summary [Mouse]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Is active in cornified envelope. Is expressed in epidermis; palmar pad; and skin. Orthologous to human KRT77 (keratin 77). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt77 |
| Official Name | keratin 77 [Source:MGI Symbol;Acc:MGI:3588209] |
| Ensembl ID | ENSMUSG00000067594 |
| Bio databases IDs | |
| Aliases | keratin 77 |
| Synonyms | 4732484G22Rik, CK-1B, K1B, K1emb, K77, Kb39, keratin 77, KRT1B, Krt239, mK1b |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt77 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Intermediate filament protein
- Keratin type II head
- FlgN protein
Pathways
Biological processes and signaling networks where the Krt77 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Krt77 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- keratinization
- intermediate filament organization
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- extracellular vesicular exosome
- keratin filament
- cytoskeleton
- cytosol
Molecular Function
What the gene product does at the molecular level
- structural constituent of epidermis
- protein binding