Fam120a Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be located in cytosol. Predicted to be active in nucleus. Is expressed in central nervous system; liver; and retina. Orthologous to human FAM120A (family with sequence similarity 120 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam120a |
| Official Name | family with sequence similarity 120, member A [Source:MGI Symbol;Acc:MGI:2446163] |
| Ensembl ID | ENSMUSG00000038014 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 120, member A |
| Synonyms | C9orf10, family with sequence similarity 120 member A, family with sequence similarity 120, member A, HBVPTPAP, LOC679485, OSSA, RGD1306643, Similar to protein C9orf10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam120a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver metastasis
- major depression
- post-traumatic stress disorder
- irritable bowel syndrome
- neuroticism
- colon cancer
- schizophrenia
- insomnia
- neurotic disorder
- myocardial infarction
role in cell
- proliferation
- formation
- expression in
- survival
- activation in
- growth
- binding in
- formation in
- migration
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- ribosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam120a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- membrane
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding