Gpr31b Gene Summary [Mouse]
Enables bioactive lipid receptor activity. Involved in several processes, including negative regulation of inflammatory response; response to ischemia; and response to molecule of bacterial origin. Predicted to be located in plasma membrane. Orthologous to human GPR31 (G protein-coupled receptor 31). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr31b |
| Official Name | G protein-coupled receptor 31, D17Leh66b region [Source:MGI Symbol;Acc:MGI:1354372] |
| Ensembl ID | ENSMUSG00000071311 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 31, D17Leh66b region |
| Synonyms | 12-HETER, Gpr31b, Gpr31c, GPR31c(t), G protein-coupled receptor 31, G protein-coupled receptor 31, D17Leh66b region, HETER, HETER1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr31b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- bioactive lipid receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- arachidonic acid binding
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Gpr31b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr31b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to molecule of bacterial origin
- response to ischemia
- G-protein coupled receptor signaling pathway
- negative regulation of inflammatory response
- lipid metabolic process
- response to acidity
- positive regulation of immune response
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- bioactive lipid receptor activity
- arachidonic acid binding