Adam1a Gene Summary [Mouse]
Predicted to enable metalloendopeptidase activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in membrane raft. Orthologous to human ADAM1A (ADAM metallopeptidase domain 1A (pseudogene)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adam1a |
| Official Name | a disintegrin and metallopeptidase domain 1a [Source:MGI Symbol;Acc:MGI:2429504] |
| Ensembl ID | ENSMUSG00000072647 |
| Bio databases IDs | |
| Aliases | a disintegrin and metallopeptidase domain 1a |
| Synonyms | ADAM1, ADAM metallopeptidase domain 1a, a disintegrin and metallopeptidase domain 1a, fertilin alpha, fertilin α, Ftna, PH-30a |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adam1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Reprolysin family propeptide
- peptidase
- protein binding
- EGF-like domain
- disintergrin domain
- Myxococcus cysteine-rich repeat
- ZnMc
- ADAM cysteine-rich
- Metallo-peptidase family M12B Reprolysin-like
- Reprolysin (M12B) family zinc metalloprotease
- Disintegrin
- disintegrin-like domain
- cysteine rich domain
Pathways
Biological processes and signaling networks where the Adam1a gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- membrane rafts