Syce3 Gene Summary [Mouse]

Involved in reciprocal meiotic recombination; spermatogenesis; and synaptonemal complex assembly. Acts upstream of or within positive regulation of apoptotic process; positive regulation of developmental process; and positive regulation of reproductive process. Located in central element. Is expressed in embryo; ovary; and testis. Orthologous to human SYCE3 (synaptonemal complex central element protein 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Syce3
Official Name
synaptonemal complex central element protein 3 [Source:MGI Symbol;Acc:MGI:1922709]
Ensembl ID
ENSMUSG00000078938
Bio databases IDs NCBI: 75459 Ensembl: ENSMUSG00000078938
Aliases synaptonemal complex central element protein 3
Synonyms 1700007E06Rik, C22orf41, LOC679198, synaptonemal complex central element protein 3, THEG2, TSEG-2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syce3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Synaptonemal complex central element protein 3

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • azoospermia
  • age-related hearing loss
regulated by
role in cell
  • apoptosis
  • formation
  • abnormal morphology
  • meiosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • chromosome
  • nucleoplasm
  • synaptonemal complexes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Syce3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • germ cell programmed cell death
  • reciprocal meiotic recombination
  • spermatogenesis
  • positive regulation of apoptotic process
  • synaptonemal complex assembly
  • apoptotic process
  • positive regulation of reproductive process
  • positive regulation of developmental process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • central element
  • chromosome

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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