Tmsb10 Gene Summary [Mouse]
Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration. Predicted to act upstream of or within actin cytoskeleton organization. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; heart; and sensory organ. Orthologous to human TMSB10 (thymosin beta 10). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmsb10 |
| Official Name | thymosin, beta 10 [Source:MGI Symbol;Acc:MGI:109146] |
| Ensembl ID | ENSMUSG00000079523 |
| Bio databases IDs | |
| Aliases | thymosin, beta 10 |
| Synonyms | AW544206, MIG12, Ptmb10, TB10, THYb10, Thymosin beta10, thymosin, beta 10, thymosin β 10, thymosin, β 10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmsb10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WH2
- actin monomer binding
- protein binding
- Thymosin beta-4 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- renal clear cell adenocarcinoma
- renal clear cell cancer
- diabetic nephropathy
- dermatomyositis
- endometriosis
role in cell
- apoptosis
- growth
- organization
- development
- disruption
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmsb10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sequestering of actin monomers
- actin filament organization
- regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin monomer binding