Shkbp1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Involved in positive regulation of epidermal growth factor receptor signaling pathway. Predicted to be located in lysosome. Is expressed in cerebral cortex intermediate zone and cortical plate. Orthologous to human SHKBP1 (SH3KBP1 binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Shkbp1 |
| Official Name | Sh3kbp1 binding protein 1 [Source:MGI Symbol;Acc:MGI:2385803] |
| Ensembl ID | ENSMUSG00000089832 |
| Bio databases IDs | |
| Aliases | Sh3kbp1 binding protein 1 |
| Synonyms | B930062H15Rik, LOC92799, PP203, RGD1309281, Sb1, SH3KBP1 binding protein 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Shkbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Shkbp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of epidermal growth factor receptor signaling pathway
- protein homooligomerization
Cellular Component
Where in the cell the gene product is active
- lysosome
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding