Ugt1a10 Gene Summary [Mouse]
Predicted to enable several functions, including monocarboxylic acid binding activity; protein dimerization activity; and protein kinase C binding activity. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and nose. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ugt1a10 |
| Official Name | UDP glycosyltransferase 1 family, polypeptide A10 [Source:MGI Symbol;Acc:MGI:3580642] |
| Ensembl ID | ENSMUSG00000090165 |
| Bio databases IDs | |
| Aliases | UDP glycosyltransferase 1 family, polypeptide A10 |
| Synonyms | A13, HLUGP4, LOC100048744, LUGP4, mUGTBr/P, UDP glucuronosyltransferase 1 family, polypeptide A9, UDP glucuronosyltransferase family 1 member A8, UDP glucuronosyltransferase family 1 member A9, UDP glycosyltransferase 1 family, polypeptide A10, UDPGT, UDPGT 1-8, UDPGT 1-9, Ugt1, UGT1-09, UGT1-9, Ugt1a10, Ugt1a12, Ugt1a13, Ugt1a8, UGT1A9S, UGT1AI, UGT-1I, UGTP4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ugt1a10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glycosyltransferase family 1 and related proteins with GTB topology
- fatty acid binding
- enzyme inhibitor activity
- protein kinase C binding
- enzyme binding
- enzyme
- retinoid binding
- protein binding
- identical protein binding
- UDP-glucoronosyl and UDP-glucosyl transferase
- steroid binding
- glucuronosyltransferase
- binding protein
- glycosyltransferase, MGT family
- protein homodimerization
- protein heterodimerization
Pathways
Biological processes and signaling networks where the Ugt1a10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hepatocellular carcinoma
- insomnia
- epithelial cancer
- liver cancer
- cutaneous melanoma
- cutaneous melanoma cancer
- diarrhea
regulated by
- tetrachlorodibenzodioxin
- rosiglitazone
- dexamethasone
- troglitazone
- rifampin
- ritonavir
- PROX1
- pirinixic acid
- choline fenofibrate
- fenofibrate
regulates
- beta-estradiol
- estrogen
- 12-hydroxyeicosatetraenoic acid
- ICRF 505
- SN-38
- bilirubin
- flavone
- opioid
- carboxylic acid
- propofol
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- microsome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ugt1a10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- flavonoid glucuronidation
- flavone metabolic process
- xenobiotic glucuronidation
- cellular glucuronidation
- liver development
- xenobiotic metabolic process
- retinoic acid metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- retinoic acid binding
- protein homodimerization activity
- protein heterodimerization activity
- glucuronosyltransferase activity
- enzyme binding