Churc1 Gene Summary [Mouse]
Predicted to enable DNA binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway. Predicted to act upstream of or within mesoderm development and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in brain; cranial ganglion; and dorsal root ganglion. Orthologous to human CHURC1 (churchill domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Churc1 |
| Official Name | churchill domain containing 1 [Source:MGI Symbol;Acc:MGI:1923684] |
| Ensembl ID | ENSMUSG00000090258 |
| Bio databases IDs | |
| Aliases | churchill domain containing 1 |
| Synonyms | 1700030P15Rik, C14orf52, chch, churchill domain containing 1, My015 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Churc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- protein binding
- DNA binding
- Churchill protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Churc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- fibroblast growth factor receptor signaling pathway
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding