Sfta2 Gene Summary [Mouse]
Predicted to be located in Golgi apparatus; extracellular region; and transport vesicle. Orthologous to human SFTA2 (surfactant associated 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sfta2 |
| Official Name | surfactant associated 2 [Source:MGI Symbol;Acc:MGI:3643293] |
| Ensembl ID | ENSMUSG00000090509 |
| Bio databases IDs | |
| Aliases | surfactant associated 2 |
| Synonyms | E030032D13Rik, EG433102, GSGL541, SFTPG, SP-G, surfactant associated 2, UNQ541 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sfta2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Surfactant-associated protein 2
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- asthma
- schizophrenia
- pervasive developmental disorder
- small cell lung carcinoma
- small cell lung cancer
- systemic lupus erythematosus
- peptic ulcer disease
- chronic interstitial cystitis
- eosinophilic esophagitis
regulated by
- lipopolysaccharide
- budesonide
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- secretory vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sfta2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- transport vesicle
- extracellular region