Nmd3 Gene Summary [Mouse]

Predicted to enable protein-macromolecule adaptor activity and ribosomal large subunit binding activity. Predicted to be involved in positive regulation of RNA biosynthetic process; positive regulation of protein localization to nucleolus; and ribosomal large subunit export from nucleus. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human NMD3 (NMD3 ribosome export adaptor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Nmd3
Official Name
NMD3 ribosome export adaptor [Source:MGI Symbol;Acc:MGI:2140103]
Ensembl ID
ENSMUSG00000027787
Bio databases IDs NCBI: 97112 Ensembl: ENSMUSG00000027787
Aliases NMD3 ribosome export adaptor
Synonyms CGI-07, NMD3 ribosome export adaptor, RGD1308468
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nmd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NMD3 family
  • protein binding activity, bridging
  • ribosomal large subunit binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nmd3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal large subunit export from nucleus
  • positive regulation of protein binding
  • protein transport

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • membrane
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • ribosomal large subunit binding
  • protein binding, bridging

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