Strit1 Gene Summary [Mouse]
Enables enzyme activator activity. Involved in positive regulation of calcium ion transport and regulation of striated muscle contraction. Acts upstream of or within positive regulation of calcium ion import. Located in sarcoplasmic reticulum membrane. Orthologous to human STRIT1 (small transmembrane regulator of ion transport 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Strit1 |
| Official Name | small transmembrane regulator of ion transport 1 [Source:MGI Symbol;Acc:MGI:5593461] |
| Ensembl ID | ENSMUSG00000103476 |
| Bio databases IDs | |
| Aliases | small transmembrane regulator of ion transport 1 |
| Synonyms | DWORF, Gm34302, LOC100508770, RP11 451G42, small transmembrane regulator of ion transport 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Strit1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- enzyme activator activity
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sarcoplasmic reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Strit1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of slow-twitch skeletal muscle fiber contraction
Cellular Component
Where in the cell the gene product is active
- sarcoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- enzyme activator activity