Pcdha8 Gene Summary [Mouse]
Predicted to be involved in cell adhesion. Predicted to act upstream of or within heart development. Located in membrane. Is expressed in brain and cerebral cortex. Orthologous to human PCDHA9 (protocadherin alpha 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcdha8 |
| Official Name | protocadherin alpha 8 [Source:MGI Symbol;Acc:MGI:2681879] |
| Ensembl ID | ENSMUSG00000103800 |
| Bio databases IDs | |
| Aliases | protocadherin alpha 8 |
| Synonyms | PCDH-ALPHA8, protocadherin alpha 8, protocadherin α 8 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdha8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- Cadherin C-terminal cytoplasmic tail, catenin-binding region
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdha8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- cell adhesion
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding