Pcdha7 Gene Summary [Mouse]

Enables calcium ion binding activity and identical protein binding activity. Involved in cell-cell recognition and homophilic cell adhesion via plasma membrane adhesion molecules. Located in plasma membrane. Is expressed in alimentary system; autopod; nervous system; and sensory organ. Orthologous to human PCDHA7 (protocadherin alpha 7) and PCDHA9 (protocadherin alpha 9). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pcdha7
Official Name
protocadherin alpha 7 [Source:MGI Symbol;Acc:MGI:1298369]
Ensembl ID
ENSMUSG00000104318
Bio databases IDs NCBI: 12939 Ensembl: ENSMUSG00000104318
Aliases protocadherin alpha 7
Synonyms CNR4, CNRN4, CNRS4, CRNR4, PCDH-ALPHA7, protocadherin alpha 7, protocadherin α 7
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdha7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin-like
  • calcium ion binding
  • Cadherin repeat-like domain
  • protein binding
  • identical protein binding
  • Cadherin C-terminal cytoplasmic tail, catenin-binding region

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • adhesion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdha7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nervous system development
  • cell adhesion
  • homophilic cell adhesion
  • cell-cell recognition

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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