Sox2ot Gene Summary [Mouse]
Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; neural ectoderm; and sensory organ. Orthologous to human SOX2-OT (SOX2 overlapping transcript). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Sox2ot |
| Official Name | SOX2 overlapping transcript (non-protein coding) [Source:MGI Symbol;Acc:MGI:2444112] |
| Ensembl ID | ENSMUSG00000105265 |
| Bio databases IDs | |
| Aliases | SOX2 overlapping transcript (non-protein coding) |
| Synonyms | B230215L15Rik, SOX2 overlapping transcript (non-protein coding) |
| Species | Mouse, Mus musculus |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- Mir122a/b
- SMAD3
- mir-8 (includes others)
- miR-330-5p (and other miRNAs w/seed CUCUGGG)
- miR-194-5p (miRNAs w/seed GUAACAG)
disease
- metastasis
- heart failure
- cognitive impairment
- fibrosis
- cardiac fibrosis
- diabetic nephropathy
- streptozotocin-induced diabetic nephropathy
- myocardial injury
- kidney injury
regulated by
- D-glucose
- isoprenaline
- FBN1
role in cell
- expression in
- apoptosis
- proliferation
- phosphorylation in
- quantity
- migration
- invasion by
- epithelial-mesenchymal transition
- sphere formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown