Cep85l Gene Summary [Rat]
Predicted to be involved in neuron migration. Predicted to be located in pericentriolar material. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in lissencephaly 10. Orthologous to human CEP85L (centrosomal protein 85 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep85l |
| Official Name | centrosomal protein 85-like [Source:RGD Symbol;Acc:2319745] |
| Ensembl ID | ENSRNOG00000000414 |
| Bio databases IDs | |
| Aliases | centrosomal protein 85-like |
| Synonyms | 1700003O08Rik, bA57K17.2, C6orf204, centrosomal protein 85-like, Gm9766, LIS10, NY-BR-15 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep85l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ciliary protein causing Leber congenital amaurosis disease
- Transforming acidic coiled-coil-containing protein (TACC), C-terminal
- Growth-arrest specific micro-tubule binding
- protein binding
- Spindle pole body component Spc42p
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- renal cell carcinoma
- dilated cardiomyopathy 1p
- familial hypertrophic cardiomyopathy type 18
- hypertrophic cardiomyopathy
- valvulopathy
- lissencephaly 10
- posterior predominant lissencephaly
- atrial fibrillation
- cardiomyopathy
- intrinsic cardiomyopathy
regulated by
role in cell
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pericentriolar regions
- centrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep85l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuron migration
Cellular Component
Where in the cell the gene product is active
- pericentriolar material
- centrosome
- cytoplasm