Evi5l Gene Summary [Rat]
Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in negative regulation of cilium assembly and positive regulation of GTPase activity. Orthologous to human EVI5L (ecotropic viral integration site 5 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Evi5l |
| Official Name | ecotropic viral integration site 5-like [Source:RGD Symbol;Acc:1561962] |
| Ensembl ID | ENSRNOG00000001034 |
| Bio databases IDs | |
| Aliases | ecotropic viral integration site 5-like |
| Synonyms | 1700084G18Rik, 2310039H16Rik, 3110007G05Rik, B130050I23Rik, ecotropic viral integration site 5-like, LOC102555038, RGD1561962 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Evi5l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab-GTPase-TBC domain
- TPR/MLP1/MLP2-like protein
- Domain in Tre-2, BUB2p, and Cdc16p
- enzyme binding
- GTPase activator
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Evi5l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of GTPase activity
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity
- small GTPase binding