Fryl Gene Summary [Rat]

Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be active in cell cortex and site of polarized growth. Orthologous to human FRYL (FRY like transcription coactivator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fryl
Official Name
FRY like transcription coactivator [Source:RGD Symbol;Acc:1311309]
Ensembl ID
ENSRNOG00000002248
Bio databases IDs NCBI: 364144 Ensembl: ENSRNOG00000002248
Aliases FRY like transcription coactivator
Synonyms 2010313D22RIK, 2310004H21RIK, 2510002A14RIK, 9030227G01RIK, AF4p12, FRY like transcription coactivator, KIAA0826, LOC231291, LOC285527, LOC728298, mKIAA0826, MOR2, PCBS, RGD1311309
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fryl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cell morphogenesis N-terminal
  • Cell morphogenesis C-terminal
  • protein binding
  • Furry protein C-terminal
  • Cell morphogenesis central region

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • migraines
  • COVID-19
  • diabetic nephropathy
  • scarlet fever
regulated by
  • decitabine
  • trichostatin A
  • RHO
  • CD24
  • tazemetostat
  • SP2509
regulates
role in cell
  • mutation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fryl gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron projection development
  • cell morphogenesis

Cellular Component

Where in the cell the gene product is active
  • site of polarized growth
  • cell cortex

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.