FRYL Gene Summary [Human]

Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be active in cell cortex and site of polarized growth. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
FRYL
Official Name
FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]
Ensembl ID
ENSG00000075539
Bio databases IDs NCBI: 285527 Ensembl: ENSG00000075539
Aliases FRY like transcription coactivator, mor2 cell polarity protein homolog (S. pombe)
Synonyms 2010313D22RIK, 2310004H21RIK, 2510002A14RIK, 9030227G01RIK, AF4p12, FRY like transcription coactivator, KIAA0826, LOC231291, LOC285527, LOC728298, mKIAA0826, MOR2, PCBS, RGD1311309
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FRYL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cell morphogenesis N-terminal
  • Cell morphogenesis C-terminal
  • protein binding
  • Furry protein C-terminal
  • Cell morphogenesis central region

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • migraines
  • COVID-19
  • diabetic nephropathy
  • scarlet fever
regulated by
  • decitabine
  • trichostatin A
  • RHO
  • CD24
  • tazemetostat
  • SP2509
regulates
role in cell
  • mutation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human FRYL gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron projection development
  • cell morphogenesis

Cellular Component

Where in the cell the gene product is active
  • site of polarized growth
  • cell cortex

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.