Fip1l1 Gene Summary [Rat]
Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human FIP1L1 (factor interacting with PAPOLA and CPSF1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fip1l1 |
| Official Name | factor interacting with PAPOLA and CPSF1 [Source:RGD Symbol;Acc:1309336] |
| Ensembl ID | ENSRNOG00000002275 |
| Bio databases IDs | |
| Aliases | factor interacting with PAPOLA and CPSF1 |
| Synonyms | 1300019H17RIK, 1300019h17Riken, DKFZp586K0717, factor interacting with PAPOLA and CPSF1, FIP1, hFip1, Rhe, Rje |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fip1l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fip1 motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- tumorigenesis
- idiopathic hypereosinophilic syndrome
- tinnitus
role in cell
- number
- apoptosis
- proliferation
- cell viability
- differentiation
- colony formation
- transformation
- upregulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fip1l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- mRNA cleavage and polyadenylation specificity factor complex
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding