Mospd1 Gene Summary [Rat]

Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Mospd1
Official Name
motile sperm domain containing 1 [Source:RGD Symbol;Acc:1359486]
Ensembl ID
ENSRNOG00000002332
Bio databases IDs NCBI: 317312 Ensembl: ENSRNOG00000002332
Aliases motile sperm domain containing 1
Synonyms 1810018L05Rik, DJ473B4, Major Sperm Domain, motile sperm domain containing 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mospd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • MSP (Major sperm protein) domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • beta-estradiol
  • budesonide
regulates
  • RNA polymerase II
  • DNA promoter
  • DNA endogenous promoter

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • cellular membrane
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mospd1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription from RNA polymerase II promoter
  • cell differentiation
  • positive regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • nucleus
  • perinuclear region of cytoplasm
  • cytoplasm
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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