Tomm40l Gene Summary [Rat]

Enables mitochondrion targeting sequence binding activity and preprotein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Part of mitochondrial outer membrane translocase complex. Orthologous to human TOMM40L (translocase of outer mitochondrial membrane 40 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tomm40l
Official Name
translocase of outer mitochondrial membrane 40 like [Source:RGD Symbol;Acc:1562006]
Ensembl ID
ENSRNOG00000003398
Bio databases IDs NCBI: 304971 Ensembl: ENSRNOG00000003398
Aliases translocase of outer mitochondrial membrane 40 like
Synonyms RGD1562006, TOMM40B, translocase of outer mitochondrial membrane 40-like
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tomm40l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Eukaryotic porin
  • Eukaryotic porin family that forms channels in the mitochondrial outer membrane
  • protein binding
  • signal sequence binding

Pathways

Biological processes and signaling networks where the Tomm40l gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • IgA nephropathy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial outer membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tomm40l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ion transport
  • protein import into mitochondrial matrix

Cellular Component

Where in the cell the gene product is active
  • pore complex
  • macromolecular complex
  • mitochondrial outer membrane translocase complex

Molecular Function

What the gene product does at the molecular level
  • mitochondrion targeting sequence binding
  • porin activity
  • protein transmembrane transporter activity
  • preprotein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.