TOMM40L Gene Summary [Human]
Predicted to enable protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TOMM40L |
| Official Name | translocase of outer mitochondrial membrane 40 like [Source:HGNC Symbol;Acc:HGNC:25756] |
| Ensembl ID | ENSG00000158882 |
| Bio databases IDs | |
| Aliases | translocase of outer mitochondrial membrane 40 like |
| Synonyms | RGD1562006, TOMM40B, translocase of outer mitochondrial membrane 40-like |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TOMM40L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Eukaryotic porin
- Eukaryotic porin family that forms channels in the mitochondrial outer membrane
- protein binding
- signal sequence binding
Pathways
Biological processes and signaling networks where the TOMM40L gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TOMM40L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transport
- protein import into mitochondrial matrix
Cellular Component
Where in the cell the gene product is active
- pore complex
- macromolecular complex
- mitochondrial outer membrane translocase complex
Molecular Function
What the gene product does at the molecular level
- mitochondrion targeting sequence binding
- porin activity
- protein transmembrane transporter activity
- preprotein binding