Tmed7 Gene Summary [Rat]

Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Tmed7
Official Name
transmembrane p24 trafficking protein 7 [Source:RGD Symbol;Acc:727954]
Ensembl ID
ENSRNOG00000003691
Bio databases IDs NCBI: 252889 Ensembl: ENSRNOG00000003691
Aliases transmembrane p24 trafficking protein 7
Synonyms 3930401E15Rik, 5830493P14Rik, CGI-109, LOC679060, p24g3, p24gamma3, p27, Tag, TRAM, transmembrane p24 trafficking protein 7
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmed7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytoplasmic domain
  • protein binding
  • emp24/gp25L/p24 family/GOLD

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • neonatal late-onset sepsis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • pH resistant lipid raft fraction
  • cellular membrane
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • ER-to-Golgi intermediate compartment
  • endoplasmic reticulum membrane
  • Golgi membrane
  • transport vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmed7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport
  • Golgi organization
  • intracellular protein transport

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • endoplasmic reticulum
  • Golgi membrane
  • ER to Golgi transport vesicle
  • Golgi apparatus
  • transport vesicle
  • endoplasmic reticulum-Golgi intermediate compartment
  • COPII vesicle coat
  • COPI vesicle coat
  • endoplasmic reticulum-Golgi intermediate compartment membrane

Molecular Function

What the gene product does at the molecular level
  • cargo receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.